Review
Open access
Jul 2026
Lipid metabolic plasticity in glioblastoma: mechanisms, tumor microenvironment remodeling, and therapeutic opportunities
Glioblastoma (GBM) is the most aggressive primary brain tumor and remains associated with poor prognosis despite multimodal treatment. Increasing evidence indicates that lipid metabolic reprogramming is a critical hallmark of GBM progression and therapeutic resistance. Beyond supporting membrane biosynthesis and energy...
Wei-Qi Wu, Minying Liu, Qianting Lv et al.
· Frontiers in Oncology · 0 citations