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Author

Junhao Xiong

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Jul 2026

Property guidance for protein sequence generative models with ProteinGuide.

ProteinGuide is applied jointly with wet-lab data generation to increase the editing activity of an adenine base editor in vivo, resulting in a base editor with higher editing efficiency than was previously achieved using seven rounds of directed evolution.

Junhao Xiong, Ishan Gaur, Maria Lukarska et al. · 1 citation

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