Aug 2026
Single-cell Transcriptome-wide Mendelian Randomization and Colocalization Converge on Astrocytic TRIM66 as a Candidate Driver and Potential Therapeutic Target for Trigeminal Neuralgia.
Astrocyte-specific regulation of TRIM66 may contribute to TN pathogenesis through neuroinflammatory pathways, offering a cell-type-resolved mechanistic perspective that complements existing models of TN biology.
Hong Ye, Chao-Ya Jiang, Zhenyan Xu et al.
· Current Medicinal Chemistry · 0 citations