Jul 2026
Structure-alignment-driven cross-graph modeling for functional RNA design
Shengfan Wang, Jun Wang, Xiaojian Liu et al.
· Nature Computational Science · 1 citation
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Jul 2026
IgGM2: An All-Atom Foundation Model for Adaptive Immune Receptor Design
IgGM2 follows a structure-to-design strategy: it first learns how immune receptors are positioned around fixed target structures, and then transfers this target-conditioned structural prior to CDR design, allowing frame-work geometry to adapt to designed CDRs without separate inverse folding or external sidechain packing.
Jian Ma, Fandi Wu, Lin Yao et al.
· bioRxiv · 0 citations