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Author

Junchao Cai

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Open access Aug 2026

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

ABSTRACT Despite substantial progress in KRAS‐targeted therapies, specific inhibitors of the KRAS G13D mutant remain unavailable. In a retrospective analysis, we found a notable downregulation of glutathione peroxidase 2 (GPX2) in KRAS G13D‐ mutant colorectal cancer (CRC), which correlated with poor outcomes. We hypoth...

Xiaoting Liu, Chong Wu, Shiyao Song et al. · 0 citations
Open access Jul 2026

A USP15/KRT17-associated 13-gene prognostic cluster and functional validation in EGFR-mutant lung adenocarcinoma.

A 13-gene prognostic cluster associated with poor survival in EGFR-mutant LUAD is identified and the EGFR-regulated USP15/KRT17 axis is position as a novel framework for patient risk stratification, with potential implications for guiding targeted therapeutic strategies.

Jia-ming Huang, Yi Huang, Qiurong Yuan et al. · 0 citations

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