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Jun-Yuan Wei

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Open access Oct 2026

Extracellular lactate enhances IL-10 transcription via H4K5 lactylation and promotes an A2-like reactive-astrocyte phenotype after ischemic stroke.

Elevated extracellular lactate in the acute phase of ischemic stroke drove RACs toward an A2-like phenotype through the Yes-associated protein 1 (YAP1)/STAT3/IL-10 and YAP1/SIRT1/H4K5la signaling axes.

Jun-Yuan Wei, Yu-Meng Si, Ji Li et al. · 0 citations

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