Oct 2026
Acacetin alleviates pyroptosis, inflammatory response, and oxidative stress in renal tubular epithelial cells caused by kidney stone via targeting GPR35.
Nephrolithiasis, particularly calcium oxalate (CaOx) stones, remains a global health burden with limited pharmacological options for recurrence prevention. In this study, we investigated the therapeutic mechanism of acacetin (ACA) using both in vitro (COM-stimulated HK-2 cells) and in vivo (glyoxylate-induced mice) mod...
Lei Jiang, Qing-Yan Xia, Zhong-Wen Hong et al.
· International Immunopharmaco... · 0 citations