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Open access Sep 2026

Lysosome-Bursting Calcium Carbonate Nanoparticles Amplify Immunogenic Cell Death via Synergistic Phototherapy and Calcium Overload for Immune Checkpoint Blockade

Immunogenic cell death (ICD) induction is a promising strategy to enhance cancer immunotherapy, yet its efficacy is often limited by insufficient immune activation. Herein, we develop a lysosome-bursting calcium carbonate nanoplatform (cRGD/MD@ICN) co-loaded with the photosensitizer indocyanine green (ICG) and a PD-L1...

Fei-Fei Cui, Qi-Fan Wu, Ren-Jie Li et al. · 0 citations

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