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Author

Junyao Zhang

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2 papers indexed here

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Open access Aug 2026

TFEB Deficiency Impairs Male Fertility Through Mitochondrial Dysfunction.

Transcription Factor EB (TFEB) is widely recognized as a key transcription factor regulating lysosomal biogenesis and autophagy. Although the TFEB gene is highly expressed in the testes, the mechanism by which it affects male fertility remains unclear. Here, we report that spermatogonia-specific deletion of TFEB in mic...

Hong-Xia Li, Guo-Qing Zhao, Ruo-Jun Zong et al. · 0 citations
Jul 2026

Lactate-associated H3K18 lactylation is involved in IGF2BP2-mediated MARCKSL1 mRNA stabilization and inflammatory signaling in LPS-induced acute lung injury.

The findings decipher a novel H3K18la/IGF2BP2/MARCKSL1 signaling cascade that integrates metabolic reprogramming with m6A epitranscriptomics in ALI, highlighting IGF2BP2 as a promising target for preventive intervention in airway epithelial inflammation.

Yangdi Peng, Jun-Yao Zhang, Yang Yang et al. · 0 citations

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