Ent-abietane diterpenoid Enantiomers from Euphorbia helioscopia inhibits liver fibrosis via suppressing the TGF-β1/smad pathway
Despite abietane diterpenoids exhibit various biological activities, their anti-fibrotic activity has rarely been investigated. In the study, 19 diterpenoids (twelve abietanes and seven other types) were isolated from E. helioscopia , comprising five undescribed ent -abietane type diterpenoids ( 1a , 1b , and...