TBX1 suppresses colorectal cancer cells via PPP2R2B-mediated inhibition of MAPK/ERK and PI3K/AKT pathways.
BACKGROUND Methods: To assess the impact of TBX1 on the proliferation and colony-forming capacity of colorectal cancer cells, in vitro functional investigations were carried out. Concurrently, a subcutaneous xenograft mouse model was established to determine the influence of TBX1 on tumor growth in vivo. Through a seri...