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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Jun-Ping Wen

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Sep 2026

Targeting ITIH3 inhibits oxidative stress and autophagy in renal tubular epithelial cells by regulating the HSP90B1/STAT3 axis, thereby alleviating diabetic nephropathy injury.

Diabetic nephropathy (DN) has emerged as the leading cause of end-stage renal disease, with oxidative stress injury and excessive autophagy implicated in its pathogenesis. Elevated levels of the ITIH3 protein are considered closely associated with kidney-related diseases. However, the role of ITIH3 in the progression o...

Wei-Ni Deng, Jia-Lin Jiang, Miao Lin et al. · 0 citations

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