FlowGRN+: Improving Gene Regulatory Network Inference by Spline Fitting and Manifold Projection in Conditional Flow Matching (Technical Report)
Gene regulatory networks (GRNs) are fundamental in understanding cellular dynamics and underlying mechanisms during development and disease. Although scRNA-seq technologies have enabled the collection of vast numbers of gene expression profiles at single-cell resolution, inferring GRNs from scRNA-seq data remains a sig...