Jun-Li Xie

Cellulose- and lignin-based smart hydrogels for barrier-adaptive delivery of fragile biotherapeutics: Molecular design, activity preservation, and translational considerations.

Fragile biotherapeutics-including therapeutic proteins, peptides, antibody fragments, nucleic acids, and extracellular-vesicle therapeutics-are increasingly central to precision medicine, yet their delivery is limited by conformational instability, enzymatic degradation, oxidative damage, interfacial adsorption, and po...