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Review Open access Sep 2026

Natural Products Modulate Plaque Macrophage Functional Programs in Atherosclerosis

Abstract Atherosclerosis is a chronic inflammatory and immunometabolic disease in which plaque macrophages integrate lipid-derived danger signals, metabolic stress and cell-death cues to shape foam-cell formation, necrotic-core expansion, fibrous-cap integrity and plaque vulnerability. Moving beyond the conventional M1...

Kai Yang, Shi-Yi Tao, Rui-Kang Liu et al. · 0 citations
Review Open access Aug 2026

Comparative effectiveness of dietary supplements in dilated cardiomyopathy: a systematic review and network meta-analysis

Dilated cardiomyopathy (DCM) is a major cause of heart failure and cardiovascular mortality, partly due to impaired myocardial energy metabolism. Dietary supplements may offer benefits through improved mitochondrial function and antioxidant effects, and randomized controlled trials (RCTs) suggest they can enhance...

Yi-Ying Liu, Rui-Kang Liu, Jun Li et al. · 0 citations
Open access Sep 2026

Long-term efficacy and impact on rehospitalization of Qishen granules in patients with hypertension and heart failure with reduced ejection fraction: a multicenter, randomized, double-blind, placebo-controlled trial protocol

Heart failure with reduced ejection fraction (HFrEF) represents a severe manifestation or terminal stage of various cardiac diseases. Long-term hypertension frequently leads to pathological changes such as ventricular remodeling, resulting in HFrEF. Despite continuous advancements in medications targeting hypertens...

Fu-Yuan Zhang, Zhao-Rui Cui, Zi-Rui Wang et al. · 0 citations

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