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Open access Sep 2026

Predicted STAT1-BRAF and IRF7-MET Regulatory Links Are Associated with MAPK Pathway Reactivation and Targeted Therapy Resistance in Melanoma

Resistance to BRAF inhibitors (BRAFi), alone or with MEK inhibitors (MEKi), limits durable responses in BRAF-mutant melanoma. To characterize resistance-associated cell-state evolution, we analyzed 674 melanoma cells from six mice bearing tumors from a single patient-derived BRAF V600E-mutant melanoma xenograft (PDX) l...

Hao Fu, Meng-Yao Wang, Hai-Bo Zhu et al. · 0 citations
Review Sep 2026

Network Analysis of Spiritual Care Perceptions and Empathy in Baccalaureate Nursing Students: A Holistic Nursing Perspective.

Analysis of the internal associations between spiritual care perceptions and empathy among baccalaureate nursing students revealed that spirituality and spiritual care values and attributes for spiritual care (ASC) were the central nodes and compassionate care emerged as the bridge nodes connecting spiritual care perce...

Dan-Dan Wu, Jun He · 0 citations

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