Author

Jun Chen

2 papers indexed here

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Open access Aug 2026

Cascade-coupled colorimetric-fluorescent dual-signal detection of EGFR-positive extracellular vesicles via bifunctional MOF@Pt nanozyme integrated with a CHA-CRISPR system.

A platform that integrates a bifunctional nanozyme system with a CHA-CRISPR/Cas12a cascade, achieving selective isolation and ultrasensitive detection of EGFR-positive glioma-derived EVs and offers a potentially adaptable framework for cascade-coupled dual-signal biosensing is developed.

Yan Wang, Bo-Ya Xu, Zehan Zeng et al. · Biosensors & bioelectronics · 0 citations

Sep 2026

Real-Time In Situ Imaging of Immunotherapy Efficacy: A DNA Nanowire-Based Biosensor for Granzyme A-Mediated APE1 Inactivation.

Real-time monitoring of natural killer (NK) cell-mediated cancer immunotherapy efficacy at the cellular and organismal levels remains a critical challenge, primarily due to the ultra-low abundance of Granzyme A (GzmA) delivered into target cells, its rapid spatiotemporal dynamics, and the scarcity of suitable in situ i...

Zi-Yue Qiu, Lu-Yin Zhang, Ya-Ting Hou et al. · ACS Sensors · 0 citations