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Open access Sep 2026

Coronary CT Angiography-Derived Plaque and Hemodynamic Characteristics for In-Stent Restenosis: A Self-Controlled Study.

BACKGROUND In-stent restenosis (ISR) after percutaneous coronary interventions (PCI) remains a significant challenge. AIMS This study aimed to investigate the predictive ability of coronary CT angiography (CTA) derived plaque and hemodynamic characteristics for ISR. METHODS In this retrospective study, we included...

Wei Gao, Fang Zhang, Wei-Feng Guo et al. · 0 citations
Aug 2026

Empagliflozin Reduces Post-Myocardial Infarction Inflammation via BDH1/β-Hydroxybutyrate-Mediated NF-κB Modulation in Macrophages and the Heart.

Empagliflozin (EMPA), a sodium-glucose cotransporter 2 (SGLT2) inhibitor, demonstrates cardioprotective effects in heart failure, and recent trials suggest benefits in acute myocardial infarction (MI). However, the mechanisms underlying its efficacy, particularly its impact on the post-MI inflammatory response, are not...

Ji'e Yang, Ke Meng, Guohong Wu et al. · 0 citations
Open access Aug 2026

Hepatic ChREBP Drives Cardiac Remodeling via ApoM Non-transcriptional Repression

This work identifies the hepatic ChREBP-SURF4-ApoM axis as a critical pathway in cardiac remodeling, and induction of hepatic ApoM secretion constitutes a new promising approach for treating cardiac remodeling and heart failure.

Shuang Zhang, Zhen-zhen Zhang, Zi-Han Ma et al. · 0 citations

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