Spatially resolved reaction–diffusion modeling reveals effects of intracellular spatial heterogeneity on yeast galactose network dynamics
Eukaryotic cells are spatially organized into functionally-distinct compartments. This three-dimensional (3D) organization generates intracellular heterogeneities that can modulate regulatory dynamics. Despite this knowledge of subcellular organization, most quantitative gene-regulation models still assume a well-mixed...
TIANYU WU, Marie-Christin Spindler, Abner T. Apsley et al.
· PLoS Computational Biology · 0 citations