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Julia K. Robinson

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Open access Sep 2026

Large-scale single-molecule analysis of tau proteoforms

Proteins exist as diverse proteoforms resulting from a combination of genetic variation, alternative splicing and post-translational modifications. Current methods struggle to capture this complexity at the single-molecule level. Here we introduce Iterative Mapping of proteoforms, a method that enables massively parall...

James Joly, V. Budamagunta, Zheng-Jian Zhang et al. · 1 citation

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