Open access
Jul 2026
Mechanistic insights into TAM-mediated OMP assembly in Gram-negative bacteria.
The β-barrel assembly machinery (BAM) is essential for outer membrane protein (OMP) biogenesis in Gram-negative bacteria and represents a validated target for antibiotic development. Its evolutionary relative, the translocation and assembly module (TAM), is thought to assemble OMPs but through a mechanism that remains...
Qinghua Luo, Xintan Dong, Zhaxi Zerang et al.
· Cell Reports · 0 citations