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Author

Ju-Bao Duan

2 papers indexed here

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Open access Sep 2026

DNA breathing and shape encode distinct mechanisms of transcription factor binding

Interactions between transcription factors (TFs) and DNA play a key role in regulating gene expression. While these interactions are often viewed primarily as recognition of DNA sequence motifs, several studies have shown the limitation of this approach and highlighted the impact of physical properties of DNA. Pr...

Tsu-Pei Chiu, Wei-Yu Tang, W. Butt et al. · 0 citations
Open access Sep 2026

Identification of alcohol use disorder-associated and ethanol-responsive proteins and candidate biomarkers using human cortical organoids

Genome-wide association studies of alcohol use disorder (AUD) have identified >100 loci, yet the functional impact and the downstream molecular mechanisms are not well understood. As functional effectors of genes, proteins provide direct insight into disease mechanisms. However, most proteomic alterations in postmortem...

Xin-Di Li, Andrew J. Boreland, Arpana Agrawal et al. · 0 citations

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