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Joshua Saito

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Open access Oct 2026

Increased Expression of α‐Synuclein Impairs Trafficking of the Essential SNARE Protein Synaptobrevin‐2

ABSTRACT α‐Synuclein is a presynaptic protein that has been extensively studied for its role in Parkinson's disease. Multiplication and missense variants in the gene encoding α‐synuclein are causes of familial PD, and aggregated α‐synuclein is a major component of Lewy bodies and Lewy neurites, the histopathological ha...

Elyas H. Arvell, James P. Carroll, Joshua Saito et al. · 0 citations

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