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Author

Joseph F. Cubells

2 papers indexed here

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Open access Sep 2026

The uneven landscape of cognitive domains in 22q11.2 deletion syndrome: A large consortium study

Abstract Background 22q11.2 deletion syndrome (22q11DS) is strongly associated with aberrant neurodevelopment, including decreased cognitive functioning and schizophrenia spectrum disorders (SSDs). While the different core domains of IQ have distinct clinical ramifications, their collective profile has not been well-ch...

A. Fiksinski, Rielle Wierenga, D. McDonald-McGinn et al. · 0 citations
Aug 2026

Negative symptom dimensions link cognitive impairment to global and social functioning in 22q11.2 deletion syndrome.

BACKGROUND 22q11.2 deletion syndrome (22q11DS) confers a 20-30% lifetime risk of schizophrenia, with negative symptoms associated with poorer outcomes and higher psychosis risk. High rates of neurocognitive deficits, autism spectrum traits (ASD), and attention-deficit/hyperactivity disorder (ADHD) may further complicat...

David A. Parker, Marissa Chen, Elaine F. Walker et al. · 0 citations

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