Open access
Aug 2026
Functional profiling of ovarian cancer models reveals Bcl-xL/NOTCH targeting to overcome resistance
Platinum resistance remains a major therapeutic challenge in ovarian cancer (OC) and is one of the main causes leading to disease relapse and mortality. Although PARP inhibitors have improved outcomes for a subset of patients, most women continue to rely on platinum-taxol based chemotherapy and ultimately develop recur...
Greta Gudoityte, O. Berkovska, L. Orre et al.
· npj Precision Oncology · 0 citations