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José N. Onuchic

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#protein folding Book Sep 2026

Modeling Ensembles of Genomes: An Energy Landscape Perspective

Abstract The three dimensional organization of the genome plays a critical role in gene regulation and cellular function. Unlike folded globular proteins, chromosomes exhibit high structural variability and must be described as ensembles of dynamic conformations rather than as single stable states. This chapter explore...

Vinícius Contessoto, José N. Onuchic · 0 citations

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