Structural Plasticity and Ligand Promiscuity of CYP3A4 Revealed by Cryo-EM
The routine use of cryo-EM to resolve CYP3A4 ligand-bound complexes will provide the ground truth data needed to make predictive models of drug metabolism useful in practice.
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The routine use of cryo-EM to resolve CYP3A4 ligand-bound complexes will provide the ground truth data needed to make predictive models of drug metabolism useful in practice.
An inhibitory antibody is discovered that reveals a structural latch regulating dimerization, identifying a regulatory element across the viral family.
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