Author

Jonathan Kilroy

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Jul 2026

Innate Immune Sensing of HIV Defective Provirus Transcripts Contributes to Chronic Inflammation 2266501

It is proposed a model that innate immune sensing of these transcripts activates a MAVS-dependent pathway to contribute to chronic inflammation and HIV-associated comorbidities.

Aparna Deokar, Jonathan Kilroy, H. Akiyama et al. · Journal of Immunology · 0 citations

Open access Aug 2026

Intragenic transcription from defective HIV proviruses triggers interferon responses in myeloid cells

It is proposed that defective HIV proviruses contribute to chronic inflammation in PWH through an MDA5-dependent induction of type I interferon pathways.

Jonathan Kilroy, Aparna Deokar, Samantha D. Patalano et al. · Journal of Virology · 0 citations