Sep 2026
CD11c+ microglia promote dysfunctional T cell activation in diffuse midline glioma
Austėja Balevičiūtė, C. Cuesta-Martí, Jessica Hincks et al.
· bioRxiv · 0 citations
2 papers indexed here
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It is suggested that histone H3.3 K27M mutations drive diffuse midline glioma by ablating intrinsic regional differences in oligodendrocyte development, selectively expanding immature oligodendrocyte precursor cell populations in the brainstem while disrupting normal differentiation programs.
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