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Author

Jolene K. Diedrich

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Review Open access Sep 2026

A microprotein atlas of the human frontal cortex in Alzheimer’s disease

Understanding the molecular basis of neurodegeneration requires a comprehensive map of the genome’s protein-coding output. Although thousands of small open reading frames (ORFs) are translated in the human brain, proteomic evidence for their encoded microproteins (MPs) (≤150 amino acids (aa)) remains limited. Here, we...

Brendan Miller, Eduardo Vieira de Souza, Calvin J. Lau et al. · 1 citation

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