Bioinspired Fe-Porphyrin Sites in a Porous Organic Polymer for Aerobic Oxidative Cyclization of Bioactive 2-Aminobenzoxazole.
A cytochrome P450-mimetic monodispersed Fe-porphyrin-based porous framework is designed and synthesized via a FeCl3-assisted Friedel-Crafts reaction, to combine the advantages of heterogeneous systems with enzymatic reactivity. Specifically, the Fe-porphyrin site in this material mimics the heme-center in cytochrome P4...