AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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The findings identify Ncf1/Igfbp2 signaling as a regulator of airway stem cell fitness and epithelial maturation, with implications for regenerative therapies in lung diseases such as cystic fibrosis.
Pulmonary ionocytes are rare cells in submucosal gland (SMG)–containing airways thought to have specialized ion transport properties that regulate airway surface fluid and mucus composition. The origins of pulmonary ionocytes remain unclear, but their association with airway SMGs suggests they may arise from specialize...
Keratin 7 (KRT7) is expressed in simple and ductal epithelia and is associated with epithelial plasticity during development, injury, and disease. However, the in vivo fate and regenerative behavior of KRT7⁺ cells remain poorly defined because lineage-tracing models are lacking in species that closely recapitulate huma...
The KRT7⁺ ductal niche is identified as a critical progenitor reservoir for airway development, homeostasis, and regeneration, with implications for cystic fibrosis therapies.
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