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Author

John E. Connolly

2 papers indexed here

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Open access Sep 2026

Systemic iron sequestration restricts the intratumoral CD8+ T cell landscape in pancreas cancer

Systemic iron sequestration occurs frequently in cancer due to inflammation-driven expression of the iron-regulatory hormone hepcidin. The impact of systemic iron availability on tumoral immunity is unclear. Here, we show that elevated serum hepcidin is associated with reduced survival and decreased intratumoral CD8+ T...

J. Schoenfeld, Jahi J. Noel, Christopher S. McGinnis et al. · 0 citations
Open access Oct 2026

MetagenomicsBench: A Verifiable Benchmark for Agentic Metagenomics Analysis

Metagenomics has transformed our ability to characterize microbial communities without relying on cultivation, but translating complex microbiome datasets into reliable biological conclusions remains a major analytical challenge. Although AI agents have improved substantially at software engineering and general data an...

Zhen Yang, John E. Connolly, Arjun Banerjee et al. · 0 citations

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