Open access
Sep 2026
Multiplexed embryo profiling links cellular state to zygotic genome activation in single cells
The cell cycle phase is the major source of variability in transcription within a division cycle, and combining this with the analysis of key transcription factors and chromatin modifier state enables accurate prediction of transcriptional output during zygotic genome activation in individual cells.
Max Hess, M. Wyss, Edlyn Wu et al.
· Nature Communications · 0 citations