Open access
Aug 2026
ENAH Binding to the Huntingtin Proline-Rich Domain Modulates HTT1a Assembly
It is demonstrated that ENAH–PRD interactions modulate HTT1a aggregation dynamics and the framework for investigating how EVH1-containing proteins may influence HTT1a proteostasis and neurotoxicity in Huntington′s disease is established.
Jobin Varkey, Anoop Rawat, Priyatama Pandey et al.
· bioRxiv · 0 citations