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Author

Joaquim M. G. D. Fonseca

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Open access Sep 2026

METTL3 promotes human coronavirus replication through an interferon-independent mechanism

A METTL3-directed Proteolysis Targeting Chimera (PROTAC) phenocopied STM2457, producing IFN-independent antiviral activity and ruling out off-target inhibition of viral RNA methyltransferases as a plausible explanation are defined.

Ikshitaa Dinesh, Joaquim M. G. D. Fonseca, Denise Ohnezeit et al. · 0 citations

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