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Author

João A. C. Lima

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Open access Aug 2026

Oral Relaxin Receptor Agonist AZD5462 in Participants With Chronic Heart Failure: Primary Results From the LUMINARA Trial.

Among individuals with well-treated chronic HF, the addition of oral AZD5462 was well tolerated and demonstrated encouraging effects on cardiovascular hemodynamic measures across a wide range of left ventricular ejection fraction.

J. Januzzi, J. Rosenmeier, P. Ely Pizzato et al. · 0 citations
Jul 2026

Integrated Left Ventricular Mass and Left Atrial Function for Prediction of Cardiovascular Outcomes: The Multi-Ethnic Study of Atherosclerosis (MESA).

A higher LV mass-to-LA strain ratio and its increase independently predict cardiovascular events before overt chamber abnormalities, supporting impaired atrial adaptation as an early stage of atrial myopathy.

Elio Salameh, M. Hoballah, E. Ebrahimihoor et al. · 0 citations

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