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Author

Jishnu Das

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Jul 2026

Cell cycle-coupled transcriptional network regulates human B cell fate bifurcation 2257411

Antibody response quality and durability depend on activated B cells bifurcating into plasmablast (PB) or germinal center B cell (GCBC) fates. PBs are short-lived and secrete low-affinity antibodies, whereas GCBCs undergo somatic hypermutation and selection before potentially generating long-lived plasma cells th...

Nicholas A. Pease, Jingyu Fan, S. Keshari et al. · 0 citations

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