O-GlcNAcylation at the tumor–immune interface: a metabolic post-translational code driving immune evasion and therapy resistance in cancer
Protein O-GlcNAcylation has evolved from a metabolic curiosity into a master post-translational modification that enables cancer cells to translate nutrient availability into coordinated programs of proliferation, therapy resistance, and immune evasion. In this review, we argue that hyper-O-GlcNAcylation is not merely...