Open access
Jul 2026
Integrative analysis of bulk and single-cell RNA sequencing reveals PHLDA3 as a key regulator of Hypoxic TAMs and prognostic biomarker in HNSC.
PHLDA3 serves as a robust prognostic biomarker for HNSC and drives the formation of an immunosuppressive microenvironment, highlighting a promising therapeutic target for combined metabolic-immune strategies in HNSC.
Jingxin Guo, Zi-Feng Cui, Jinhang Wang et al.
· Discover Oncology · 0 citations