IRF5 promotes the progression of ulcerative colitis by regulating macrophage polarization and Toll-like receptor signaling pathway.
Interferon regulatory factor 5 (IRF5) is genetically linked to ulcerative colitis (UC) susceptibility, yet its role in intestinal inflammation remains poorly understood. Here, we detected IRF5 expression in intestinal tissues from 29 UC patients and 10 healthy controls via immunohistochemistry and immunofluorescence. W...