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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Jing Zhang

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3 papers indexed here

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Open access Sep 2026

A low-matrix organoid-T cell co-culture platform for functional evaluation of T cell engagers in patient-derived colorectal cancer organoids

Background Colorectal cancer (CRC) remains a leading cause of cancer-related mortality, and emerging T cell engager (TCE) immunotherapies require predictive preclinical models that capture patient-specific tumour biology and tumour-immune interactions. Although patient-derived organoid (PDO)-immune co-culture systems s...

C. M. A. Pinna, K. Rakhimova, Jing Zhang et al. · 0 citations
Aug 2026

The mechanism of SOX4/IGF2BP3/TRIB3 axis inhibiting autophagy and aggravating liver injury in sepsis.

It was found that the SOX4/IGF2BP3/TRIB3 axis was upregulated in septic hepatocytes, and its knockdown alleviated LPS-induced injury and impaired autophagic flux, and this axis exacerbated LPS-induced hepatocyte injury by suppressing autophagic flux.

Wen-Jun Zhao, Jing Zhang, Liang Zhang et al. · 0 citations
Open access Aug 2026

IGF2BP3-mediated regulation of the RNA isoform and modification landscape in pancreatic cancer

Data show that IGF2BP3 is expressed consistently in PDAC, plays a dominant role in regulation of RNA splicing and modification, and supports cancer stem cell proliferation and survival, and represents an important therapeutic target in this tumour of unmet need.

Sandra Margielewska-Davies, W. Croft, H. Pearce et al. · 0 citations

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