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Author

Jingyun Li

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#protein folding Open access Oct 2026

A four-amino-acid deletion in gp41 enhances HIV-1 CRF01_AE Cluster 4 pathogenicity and fusion inhibitor resistance

ABSTRACT HIV-1 CRF01_AE Cluster 4 strains are spreading rapidly in China and Southeast Asia, yet the molecular characteristics and pathogenic mechanisms remain to be fully characterized. Here, we identified a characteristic RSSL tetrapeptide deletion in the gp41 region of CRF01_AE Cluster 4 strains. Compared with a Clu...

Dong Zhang, Jing-Wan Han, Chang Liu et al. · 0 citations
Jul 2026

Genomic Characterization of Two Novel HIV-1 CRF01_AE/CRF07_BC Unique Recombinant Forms in Shenzhen, China.

Analysis of HIV-1 samples collected from two male patients in Shenzhen suggested that the recombination between CRF01_AE and CRF07_BC continued to occur in Shenzhen, potentially contributing to the increasing genetic complexity of the local HIV-1 epidemic.

Dandan Lin, Bo Zhu, Shengya Liu et al. · 0 citations

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