Open access
Aug 2026
Orthogonal Cas13a/Cas12a cascade for one-pot amplification-free detection of miRNA-21.
This one-pot Cas13a/Cas12a cascade fluorescence biosensor enabled quantitative detection of miRNA-21 over a concentration range of 1-1000 pmol/L within 60 min, with a low detection limit of 0.66 pM.
Jing Yuan, Meng Shen, Li-Hua Ding et al.
· Talanta: The International J... · 0 citations