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Author

Jingyu Fan

2 papers indexed here

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Open access Sep 2026

Interpretable machine learning coupled to gene regulatory networks uncovers subcircuits underlying cell fate decisions

Gene regulatory networks (GRNs) model causal linkages that control cell fate decisions and differentiation transitions. Prioritizing regulatory subnetworks underlying cell state differences is of critical importance, but current methods including those reliant on topological metrics introduce circularity as the metrics...

Z. H. Rarani, S. Keshari, A. Sachan et al. · 0 citations
Jul 2026

Cell cycle-coupled transcriptional network regulates human B cell fate bifurcation 2257411

A generalizable framework for assembling and testing GRNs in the context of immune cell fate decisions is established, and previously unreported feedback loops that link cell division to fate specification are revealed.

Nicholas A. Pease, Jing-Yu Fan, S. Keshari et al. · 0 citations

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