A four-amino-acid deletion in gp41 enhances HIV-1 CRF01_AE Cluster 4 pathogenicity and fusion inhibitor resistance
ABSTRACT HIV-1 CRF01_AE Cluster 4 strains are spreading rapidly in China and Southeast Asia, yet the molecular characteristics and pathogenic mechanisms remain to be fully characterized. Here, we identified a characteristic RSSL tetrapeptide deletion in the gp41 region of CRF01_AE Cluster 4 strains. Compared with a Clu...
Dong Zhang, Jing-Wan Han, Chang Liu et al.
· Journal of Virology · 0 citations