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Review Open access Sep 2026

Extracellular vesicles in the immune regulation of hematological malignancies: mechanisms, prognostic significance, and therapeutic opportunities

The progressive cross-talk between tumor cells and the immune microenvironment, which is required for tumor growth, progression, and dissemination, has been well documented in solid cancers and is increasingly recognized in hematological malignancies. Extracellular vesicles (EVs) are now emerging as essential facilit...

Tu-Ya Wang, Jing Fu, Ye Huang et al. · 0 citations
Review Sep 2026

Patient-Derived Organoids for Hepatobiliary Cancers: Molecular Mechanisms, Translational Applications and Precision Therapeutics.

Hepatobiliary cancers are highly heterogeneous malignant tumors, and the drug resistance frequently emerges at advanced stages. Patient-derived organoids (PDOs) are three-dimensional ex vivo cultures. They can reproduce essential biological aspects of primary tumors, and play a key role in personalized oncology. With a...

Senyan Wang, Yi-Xuan Liu, Qi Liu et al. · 0 citations

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