Introduction Patients with pulmonary tuberculosis (PTB) may experience persistent immune dysregulation during anti-tuberculosis treatment, yet vaccine evaluation in this population has largely relied on humoral endpoints. Whether preserved antibody responses reflect coordinated systems-level immune activation after ina...
Zhi-Jie Jiang, Peng-Fei Jin, Xiao-Rui Nie et al.· Frontiers in Immunology· 0 citations
The findings suggest that SARS-CoV-2 antigenic evolution follows the pattern of multiple pathways within a constrained space, providing new insights into the adaptive mechanisms of Omicron-derived variants under hybrid immune pressure.
Cheng-Wei Shao, Jian-Guang Fu, Fei Deng et al.· Microorganisms· 0 citations
Heterologous boosting with Ad5-nCoV elicited more mature B cells with higher affinity and activated more abundant immune-related pathways compared to the homologous boosting with CoronaVac, which gives insights for elaborating the systemic immune landscape of heterologous-boosting COVID-19 immunization by the novel sin...
Xu Han, Hudachuan Jiang, Hui Zheng et al.· Journal of Translational Med...· 0 citations
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