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Author

Jing Wu

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Open access Sep 2026

Allotopic Expression of ND6 Restores Vision in a Mitochondrial Disease Model.

This study validates the safety and therapeutic potential of allotopic expression in vivo and provides critical mechanistic insights into its role in treating LHON and other mitochondrial diseases.

Cheng Ai, Hui-Ying Li, Jing Wu et al. · 0 citations
Review Open access Sep 2026

PERK signalling in neurodegenerative diseases: From ER stress to mitochondrial dysfunction and therapeutic opportunities

The activation mechanisms of the PERK pathway in diseases such as Alzheimer’s disease and Parkinson’s disease are reviewed, focusing on its role as a molecular bridge that converts endoplasmic reticulum stress into mitochondrial dysfunction.

Tao Xu, Sheng-Wei Jing, Jing Wu · 0 citations

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