Oct 2026
Piperlongumine alleviates colitis by promoting β-catenin proteasomal degradation to inhibit NLRP3 inflammasome activation and pyroptosis.
Ulcerative colitis is a chronic inflammatory disorder characterized by diffuse mucosal inflammation confined to the colon and rectum. Long pepper is a widely used condiment for stews and barbecues and is known for its potential nutritional and medicinal value. Piperlongumine (PPL), the major active component of long pe...
Yu-Chen Li, Jia-Jie Jiang, Yu-Huan Zhou et al.
· European Journal of Pharmaco... · 0 citations